Hoshide studied mechanical and aerospace engineering before entering Japanese human-spaceflight work. Before flying, he supported H-II launch vehicle — open definition development, the Japanese Experiment Module, and HTV operations.

His flight record spans three spacecraft systems: Space Shuttle Discovery on STS-124, Soyuz TMA-05M for Expeditions — open definition 32 and 33, and Crew Dragon Endeavour on SpaceX Crew-2 for Expeditions 65 and 66.

Hoshide became one of Japan's most experienced astronauts, performed four spacewalks — open definition, helped assemble and operate Kibo, and became the second Japanese commander of the ISS.

STS-124 launched on May 31, 2008 aboard STS-124 flight stack, with Hoshide serving as Mission Specialist — open definition. Soyuz TMA-05M launched on July 15, 2012 aboard Soyuz TMA-05M flight vehicle, with Hoshide serving as Flight Engineer — open definition. Hoshide's additional completed flights were SpaceX Crew-2. This mission context is drawn from the linked agency or institutional flight material and distinguishes flown service from training or backup assignments.